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Figure 5-23.
Expression of arylalkylamine N-acetyltransferase 2 (AANAT2), the rate-limiting enzyme in melatonin synthesis, in the medaka pineal organ (Iigo et al., unpublished data). AANAT2 was found to be expressed in pineal photoreceptor cells facing the lumen by in situ hybridization histochemistry. The frontal section of the pineal organ from medaka collected at midnight was analyzed.